Ideas

October 9, 2017

Published by admin_auro at October 9, 2017

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Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: A pharmaceutical mixture encompassing Artesunate and 15-Deoxy-Delta-12,14-prostaglandin J2 (15d-PGJ2) [APGJ2] increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 09/October/2017, 11.29 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]

October 9, 2017

Published by admin_auro at October 9, 2017

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Lifespan extension therapy: Glyburide, an anti- hyperglycemic medication, increases life span via up-regulation of its target gene BubR1, 9/October/2016, 11.18 pm

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]

October 9, 2017

Published by admin_auro at October 9, 2017

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Ideas
NAFLD

Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Isoflurane [Trade name: Forane] promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 09/October/2017, 11.10 am

Significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while only 6-25% of Asian populations suffer from it; […]

October 8, 2017

Published by admin_auro at October 8, 2017

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Ideas
Stroke

Natural product-derived therapy for Stroke: Methysticin, isolated from Kava Kava, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 9/October/2017, 1.25 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]