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Ideas

May 5, 2017

Natural product therapy for Diabetic nephropathy (DN): Fisetin, found in Strawberries, Persimmons, A. greggii, and honey locust (Gleditsia triacanthos) among others, increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 5/May/2017, 7.29 am

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may […]
May 4, 2017

Natural product therapy for glucose homeostasis and TIIDM: Oxyresveratrol, isolated from Artocarpus Lakoocha, and Morus Alba among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 4/May/2017, 11.45 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
May 4, 2017

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Insulin gene enhancer protein ISL-1 increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 4/May/2017, 11.15 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows […]
May 4, 2017

Natural product-derived regenerative therapy for improving memory in aged individuals: Genistein, an isoflavone isolated from Soy products and Kudzu/Japanese arrowroot/Pueraria montana increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 4/May/2017, 10.55 pm

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
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