Ideas

August 29, 2017

 Lifespan extension therapy: Ruxolitinib (Trade name: Jakavi), a drug used in the treatment of Myelofibrosis,  prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 30/August/2017, 12.06 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
August 28, 2017

Natural product therapy for glucose homeostasis and TIIDM: Geniposide (GP), isolated from Gardenia, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/August/2017, 1.05 am

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
August 28, 2017

Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Hyperoside, isolated from Drosera Rotundifolia, and Prunella Vulgaris (Common Self-heal), among others, increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 29/August/2017, 12.38 am

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
August 28, 2017

Natural product-derived therapy for inflammation and arthritis: Epigallocatechin-3-O- gallate (EGCG) increases IL-9, increases IL-9 levels, increases proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regulation of its target genes, 28/August/2017, 11.48 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
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