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Ideas

May 6, 2017

Natural product-derived therapy for Metastatic cancers: Solasodine, found in Solanum melongena, increases the expression of metastasis promoters TPM1 (Tropomyosin 1) and Tp63, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 6/May/2017, 6.11 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
May 6, 2017

Natural product-derived therapy therapy for Stroke: Howthorn berry extract attenuates hippocampal neurons injury and ameliorates stroke damage and neurological deficits via up regulation of its target gene BDNF, 6/May/2017, 5.56 pm

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
May 5, 2017

Natural product therapy for Diabetic nephropathy (DN): Fisetin, found in Strawberries, Persimmons, A. greggii, and honey locust (Gleditsia triacanthos) among others, increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 5/May/2017, 7.29 am

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may […]
May 4, 2017

Natural product therapy for glucose homeostasis and TIIDM: Oxyresveratrol, isolated from Artocarpus Lakoocha, and Morus Alba among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 4/May/2017, 11.45 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
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