Ideas

Life-extension therapy: Hesperitin, found in Citrus fruits, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 7/February/2017, 11.01 pm
Life-extension therapy: Hesperitin, found in Citrus fruits, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 7/February/2017, 11.01 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Anticancer therapy: MiRNA-9600 increases the expression of tumor suppressor TNFAIP8L2/TIPE2, inhibits proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 7/February/2017, 10.36 pm
Anticancer therapy: MiRNA-9600 increases the expression of tumor suppressor TNFAIP8L2/TIPE2, inhibits proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 7/February/2017, 10.36 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may inhibit the expression of tumor suppressor Tumor necrosis factor (TNF)-α-induced protein…

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Regenerative therapy for improving muscle repair and strength in the elderly: Succinate, one of the components in Citric acid cycle, extract decreases the expression of HOXA9, increases skeletal muscle regeneration and improves muscle stem cells function and repair via up regulation of its target genes, 7/February/2017, 10.28 pm
Regenerative therapy for improving muscle repair and strength in the elderly: Succinate, one of the components in Citric acid cycle, extract decreases the expression of HOXA9, increases skeletal muscle regeneration and improves muscle stem cells function and repair via up regulation of its target genes, 7/February/2017, 10.28 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Faculty of Medicine, Friedrich-Schiller-University, Germany shows that “Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.” This research paper was published…

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Natural product-derived therapy for glucose homeostasis and TIIDM: Ellagic acid, found in walnuts, pecans, cranberries, raspberries, and strawberries, among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 7/February/2017, 7.04 am
Natural product-derived therapy for glucose homeostasis and TIIDM: Ellagic acid, found in walnuts, pecans, cranberries, raspberries, and strawberries, among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 7/February/2017, 7.04 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel shows that…

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Natural product-based Lifespan extension therapy: Kaemphferol, found in Aloe Vera, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 6/February/2017, 10.48 pm
Natural product-based Lifespan extension therapy: Kaemphferol, found in Aloe Vera, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 6/February/2017, 10.48 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1)…

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Molecular therapy for Bone disorders: LRRC4/NGL-2 (Leucine rich repeat containing 4/Netrin-G ligand-2) inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 6/February/2017, 10.34 pm
Molecular therapy for Bone disorders: LRRC4/NGL-2 (Leucine rich repeat containing 4/Netrin-G ligand-2) inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 6/February/2017, 10.34 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis…

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