Ideas

Natural product therapy for triple-negative breast tumors: Aloe vera extract increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 8/November/2015, 10.29 pm
Natural product therapy for triple-negative breast tumors: Aloe vera extract increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 8/November/2015, 10.29 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that “PIM1 kinase inhibition as…

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Natural product-based PD-1 pathway blockade for Human cancer therapy: Neem leaf extract inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 8/November/2016, 10.15 pm
Natural product-based PD-1 pathway blockade for Human cancer therapy: Neem leaf extract inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 8/November/2016, 10.15 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say:  A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 Enhances PD-1 Expression on…

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Natural product therapy for KRAS-mutant lung cancer: Moringa oleifera (MO) extract decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 8/November/2016, 5.22 pm
Natural product therapy for KRAS-mutant lung cancer: Moringa oleifera (MO) extract decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 8/November/2016, 5.22 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Department of Cell Biology, University of Texas Southwestern Medical Center, Texas 75390, USA shows that XPO1 can be pharmacologically targeted in KRAS-mutant lung cancer.…

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Natural product therapy for NIDDM: Avicularin, found in Polygonum aviculare, Rhododendron aureum and Taxillus kaempferi, inhibits gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, Genome-2-Bio-Medicine Discovery center (GBMD), 8/November/2016, 1.24 pm
Natural product therapy for NIDDM: Avicularin, found in Polygonum aviculare, Rhododendron aureum and Taxillus kaempferi, inhibits gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, Genome-2-Bio-Medicine Discovery center (GBMD), 8/November/2016, 1.24 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, USA; and others shows that “Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression.” This study was…

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Interleukin-based Lifespan extension therapy: IL-23 (Interleukin-23) increases life span via up-regulation of its target gene BubR1, 8/November/2016, 12.32 pm
Interleukin-based Lifespan extension therapy: IL-23 (Interleukin-23) increases life span via up-regulation of its target gene BubR1, 8/November/2016, 12.32 pm 150 150 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Natural product therapy for Breast Cancer: Rhamnetin, found in Cloves, increases the levels of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 8/November/2015, 7.25 am
Natural product therapy for Breast Cancer: Rhamnetin, found in Cloves, increases the levels of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 8/November/2015, 7.25 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A study from the Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA shows…

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