Ideas

June 15, 2017

Published by admin_auro at June 15, 2017

Categories

Cancer
Ideas

Combination therapy for enhancing the efficacy of tyrosine-kinase inhibitor (TKI) in BCR-ABL-induced Human leukemia: A therapeutic mix encompassing Ascorbate and Forodesine decreases the expression of oncoproteins c-FOS, DUSP1 and BCR-ABL, inhibits TKI resistance, restores treatment responsiveness, increases therapeutic index of anticancer drugs, and cure CML and kinase-driven cancers via up-regulation of its target gene, 16/June/2017, 2.05 am

Introduction: What they say: A study from the Division of Experimental Hematology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA; Division of Pathology, Cincinnati Children’s Hospital […]

June 15, 2017

Published by admin_auro at June 15, 2017

Categories

Laminar shear stress-based regenerative therapy for muscular atrophy: Laminar shear stress increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 16/June/2017, 1.14 am

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes […]

June 15, 2017

Published by admin_auro at June 15, 2017

Categories

Natural product-derived regenerative therapy for improving memory in aged individuals: Leaf powder of Ashwagantha increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 16/June/2017, 12.40 am

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA; Paul F. Glenn Center […]

June 15, 2017

Published by admin_auro at June 15, 2017

Categories

Natural product-based Anti-ageing and Life extension therapy: Withaferin A, isolated from Ashwagandha (Withania somnifera), increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 16/June/2017, 12.11 am

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str. Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]