Ideas

June 15, 2017

Published by admin_auro at June 15, 2017

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Molecular therapy for Inflammatory bowel disease: Zic2 (Zic Family Member 2) promotes NFKB-p50/p65 dimer formation, induces inflammatory gene expression downstream of RelA/p65, inhibits colonic pathogenesis, and stalls the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 16/June/2017, 12.04 am

Introduction: What they say: A study from the Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg, University of Mainz, Obere Zahlbarer Str, Mainz, […]

June 15, 2017

Published by admin_auro at June 15, 2017

Categories

Cancer
Ideas

Interleukin therapy for Chronic Myeloid leukaemia (CML): Interleukin-1β decreases the expression of Musashi2, inhibits cytosolic aminotransferase BCAT1 expression, decreases the intracellular production of BCAAs (Branched-chain amino acids), increases the expression of tumor suppressor genes, promotes differentiation of CML cells, and inhibits cancer progression in Myeloid leukemia via up-regulation of its target gene, 15/June/2017, 11.48 pm

Introduction: What they say: A study from the Department of Biochemistry-Molecular Biology, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, USA; […]

June 14, 2017

Published by admin_auro at June 14, 2017

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Natural product-derived therapy for glucose homeostasis and TIIDM: Salidroside, isolated from Rhodiola Rosea, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 15/June/2017, 1.05 am

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]

June 14, 2017

Published by admin_auro at June 14, 2017

Categories

Cancer
Ideas

Natural product-derived Anti-AXL therapeutics for enhancing the efficacy of chemotherapies: Combination of Honokiol and Hesperidin, found in Magnolia grandiflora and Citrus fruits, respectively, decreases the expression of the AXL receptor and its activating ligand, GAS6, increases the expression of a number of tumor suppressor genes, increases therapeutic index of anticancer drugs, suppresses tumorigenesis, migration, invasion, and metastasis via up regulation of its target gene, 15/June/2017, 1.00 am

Introduction: What they say: A study from the Department of Radiation Oncology, Stanford University School of Medicine shows that “Inhibition of the GAS6/AXL pathway augments the […]