Ideas

February 8, 2017

Molecular therapy for Myocardial Infarction: Long ncRNA CUDR (Cancer up regulated drug resistant) inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 8/February/2017, 10.54 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
February 8, 2017

Anti-metastasis therapy: MiRNA-9600 increases the expression of metastasis suppressor Sprouty1 and inhibits proliferation, invasion and metastasis of cancer cells via down regulation of its target gene, 8/February/2017, 10.23 pm

Research findings to Therapeutic opportunity:  The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of metastasis suppressor […]
February 8, 2017

Natural product-based Lifespan extension therapy: Arecoline/Areca nut extract prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 8/February/2017, 9.25 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
February 8, 2017

Natural product therapy for pulmonary arterial hypertension: EGCG (Epigallocatechin-3-gallate), one of the main components of Green tea, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 8/February/2017, 8.56 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
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