Ideas

May 24, 2017

Laminar shear stress-based therapy for glucose homeostasis and TIIDM: Laminar shear stress increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 24/May/2017, 7.30 am

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
May 24, 2017

Natural product-derived therapy for metastatic prostate cancer: Agaricus blazei Murrill (AbM) mushroom extract inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 24/May/2017, 7.29 am

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA […]
May 24, 2017

Vitamin-based anti-metastatic therapy for Notch1-overexpressing Human cancers: Δ-Tocotrienol, a form of Vitamin-E, inhibits the expression of Notch1, and adhesion molecule VCAM1, suppresses neutrophil infiltration and tumor cell adhesion to endothelium, and prevents Notch1-driven metastasis via up regulation of its target gene, 24/May/2017, 7.28 am

Introduction: What they say: A study from the Vascular Signaling and Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Vascular Biology, CBTM, Medical Faculty Mannheim, […]
May 24, 2017

Mechanical Stretch therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Mechanical Stretch therapy increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 24/May/2017, 7.26 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows […]
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