Ideas

April 10, 2017

Natural product-derived therapy for Human cancers: α-Lipoic acid, found in leafy green vegetables, increases the expression of mitochondrial protein LACTB, decreases levels of mitochondrial phosphatidylserine decarboxylase, alters mitochondrial lipid metabolism, and promotes differentiation of breast cancer cells via up-regulation of its target gene, 10/April/2017, 11. 45 pm

Introduction: What they say: A study from the Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts, USA, Department of Biology, Massachusetts Institute of Technology, […]
April 10, 2017

Natural product-derived therapy for Allergic rhinitis:Dioscin, a natural steroid saponin, inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, and eotaxin expression, among others, inhibits mucus production and alleviates allergic rhinitis via up regulation of its target gene, 10/April/2017, 11.29 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Allergic rhinitis: Dioscin, a natural steroid saponin,  inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, […]
April 10, 2017

Natural product-derived regenerative therapy for reversing diabetes: Berberine, found in Berberis, Oregon grape, Hydrastis canadensis, and Phellodendron amurense among others, increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 10/April/2017, 11.18 pm

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, […]
April 10, 2017

Amino-acid based therapy for tuberculosis:L-Leucine, a branched-chain amino acid (BCAA), deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 10/April/2017, 10.45 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
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