Ideas

April 7, 2017

Molecular therapy for ageing-associated diseases: Lithium, a mood stabilizing agent used in the treatment of Bipolar disorder, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 7/April/2017, 11.08 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
April 7, 2017

Natural product-derived therapy for Metastatic cancers: Naringenin, found in grapefruits, among others, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 7/April/2017, 8.25 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
April 7, 2017

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Oncostatin M (OSM) increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene, 7/April/2017, 6.50 am

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
April 6, 2017

Natural product-derived therapy for Allergic rhinitis: α-lipoic acid, found in Broccoli, brussel sprouts, and kali among others, inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, and eotaxin expression, among others, inhibits mucus production and alleviates allergic rhinitis via up regulation of its target gene, 6/April/2017, 11.56 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Allergic rhinitis: α-lipoic acid, found in Broccoli, brussel sprouts, and kali […]
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