Ideas

April 28, 2017

Published by admin_auro at April 28, 2017

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Ideas

Natural product therapy for TIIDM and Metabolic defects: Polydatin (PD), a longevity-promoting molecule isolated from Polygonum cuspidatum, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/April/2017, 12.08 am

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]

April 28, 2017

Published by admin_auro at April 28, 2017

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Ideas

Natural product-derived therapy for Stroke: Myricetin, isolated from Abelmoschus moschatus (Malvaceae), attenuates hippocampal neurons injury and ameliorates stroke damage and neurological deficits via up regulation of its target gene BDNF, 28/April/2017, 11.54 pm

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]

April 28, 2017

Published by admin_auro at April 28, 2017

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Ideas

Steroid based therapy for tuberculosis: Ethinylestradiol deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 28/April/2017, 11.26 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]

April 28, 2017

Published by admin_auro at April 28, 2017

Categories

Ideas

Natural product therapy for Diabetic nephropathy (DN): Oleanolic acid, found in Jawa apple, Olea Europaea, and Mirabilis Jalaba among others, increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 28/April/2017, 11.36 am

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may […]