Ideas

March 22, 2017
Published by admin_auro at March 22, 2017
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Natural product-derived therapy for Human Leukemias: Wogonin, isolated from Scutellaria baicalensis, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 22/March/2017, 6.25 pm

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms […]
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March 22, 2017
Published by admin_auro at March 22, 2017
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Amino acid-based Lifespan extension therapy: L-Leucine prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 22/March/2017, 9.14 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
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March 22, 2017
Published by admin_auro at March 22, 2017
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Anti-telomerase cancer therapy: Forsythiae Fructus extract suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 22/March/2017, 7.23 am

Introduction:  The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]
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March 21, 2017
Published by admin_auro at March 21, 2017
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MiRNA-based Life-span extension therapy: MiR-497 may increase lifespan by suppressing mTOR pathway, 21/March/2016, 11.59 pm

What is known:  It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity […]
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