Ideas

March 14, 2017
Published by admin_auro at March 14, 2017
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Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Ursolic acid, isolated from Mirabilis Jalapa, Ocimum sanctum, and Apple peels among others, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 14/March/2017, 1.07 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]
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March 14, 2017
Published by admin_auro at March 14, 2017
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Amino acid-based therapy for pulmonary fibrosis: L-Leucine decreases miR-34 expression, increases Sirtuin-1 expression, suppresses tumor suppressor p53 acetylation, prevents apoptosis in Alveolar epithelial cell (AEC), and improves pulmonary fibrosis via down regulation of its target gene, 14/March/2017, 11.34 am

What we say:  Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Amino acid-based therapy for pulmonary fibrosis: L-Leucine decreases miR-34 expression, increases Sirtuin-1 expression, suppresses tumor suppressor p53 […]
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March 13, 2017
Published by admin_auro at March 13, 2017
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Natural product-derived therapy for Metastatic cancers: Oleic acid, found in Safflower, olive, canola, Hazelnut, sunflower oils, Avacados, almond and sunflower among others, decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 13/March/2017, 11.42 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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March 13, 2017
Published by admin_auro at March 13, 2017
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Natural product-derived antiviral therapy for HIV virus: Mulberry water extract (MWE) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 13/March/2017, 5.54 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
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