Ideas

February 23, 2017
Published by admin_auro at February 23, 2017
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Natural product-derived Anti-AXL therapeutics for enhancing the efficacy of chemotherapies: Combination of Valproic acid and Deoxycholic acid, decreases the expression of the AXL receptor and its activating ligand, GAS6, increases the expression of a number of tumor suppressor genes, increases therapeutic index of anticancer drugs, suppresses tumorigenesis, migration, invasion, and metastasis via up regulation of its target gene, 23/February/2017, 10.38 pm

Introduction: What they say: A study from the Department of Radiation Oncology, Stanford University School of Medicine shows that “Inhibition of the GAS6/AXL pathway augments the […]
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February 23, 2017
Published by admin_auro at February 23, 2017
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Natural product-derived antiviral therapy for HIV virus: Shikonin, isolated from Zicao (also known as Purple gromwell, the dried root of Lithospermum erythrorhizon), increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 23/February/2017, 9.53 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
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February 23, 2017
Published by admin_auro at February 23, 2017
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Amino acid therapy for Metabolic diseases: Leucine increases the expression of Caveolin-1, stabilizes insulin receptor, promotes insulin sensitivity, incrases vasorelaxation, and decreases the risk of hyperglycemia and TIIDM via up regulation of its target gene, 23/February/2017, 9.29 pm

Introduction: What they say A study from the Institute for Molecular Systems Biology, ETH Zurich, Zurich, Switzerland shows that “MicroRNAs 103 and 107 regulate insulin sensitivity.” […]
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February 23, 2017
Published by admin_auro at February 23, 2017
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Natural product-derived therapy for Diabetic Kidney disease: Naringenin, a flavanone found in grapefruit, oranges, and water mint among others, decreases VEGF-B expression, inhibits lipid accumulation in Podocytes, promotes insulin signalling in Podocytes, induces insulin sensitivity, ameliorates renal dysfunction and alleviates diabetic kidney disease via down regulation of its target gene, 23/February/2017, 7.03 am

Introduction: What they say A study from the Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden shows that […]
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