Ideas

February 22, 2017

Published by admin_auro at February 22, 2017

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Ideas

Molecular therapy for Bone disorders: Resistin, a pro-inflammatory cytokine, inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via down-regulation of its target gene, 22/February/2017, 9.43 am

Introduction: What they say: A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone […]

February 22, 2017

Published by admin_auro at February 22, 2017

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Small molecule-based PD-1 pathway blockade for Human cancer therapy: Tumor suppressor Menin (MEN1), responsible for multiple endocrine neoplasia type 1 syndrome, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 22/February/2017, 9.33 pm

Introduction:What they say: A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]

February 21, 2017

Published by admin_auro at February 21, 2017

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Natural product-based therapy for Metastatic cancers: (6)-gingerol (6G), one of the main components of Ginger, increases the expression of BTG2 and promotes apoptosis, inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 21/February/2017, 11.16 pm

Research findings to Therapeutic opportunity: The study presented here suggests that (6)-gingerol (6G), by increasing the expression of its target genes, it may increase the expression of […]

February 21, 2017

Published by admin_auro at February 21, 2017

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MiRNA-based therapy for Metastatic human tumors: MiR-382 decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 21/February/2017, 11.08 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]