Ideas

February 5, 2017
Published by admin_auro at February 5, 2017
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Anticancer therapy: MiRNA-9600 decreases the expression of cell cycle regulator CDC25A, inhibits proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 5/February/2017, 7.50 pm

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may inhibit the expression of Cell cycle regulator […]
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February 5, 2017
Published by admin_auro at February 5, 2017
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Immune enhancement therapy: Gremlin-1 (GREM1) increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 5/February/2017, 7.24 pm

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
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February 5, 2017
Published by admin_auro at February 5, 2017
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Natural product-based Lifespan extension therapy: Casticin, found in VITEX agnus-castus, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 5/February/2017, 7.00 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
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February 5, 2017
Published by admin_auro at February 5, 2017
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Life-extension therapy: Orphan nuclear receptor Nur77/NGFI-B inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 5/February/2017, 6.47 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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