Ideas

February 15, 2017
Published by admin_auro at February 15, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Combination of Resveratrol and Metformin decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 15/February/2017, 6.17 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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February 15, 2017
Published by admin_auro at February 15, 2017
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Natural product-derived therapy for Metastatic human tumors: β-lonone, one of the main components of herb Boronia Megastigma, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 15/February/2017, 7.14 am

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
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February 15, 2017
Published by admin_auro at February 15, 2017
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Anti-telomerase cancer therapy: Guttiferone, isolated from Garcinia Cambogia, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 15/February/2017, 6.45 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
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February 14, 2017
Published by admin_auro at February 14, 2017
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Natural product-derived therapy for glucose homeostasis and TIIDM: Berberine, isolated from Berberis, Hydrastis Canadesis, and Berberis aristata, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of its target gene Sox4, 14/February/2017, 11.41 pm

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in […]
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