Ideas

February 10, 2017

Published by admin_auro at February 10, 2017

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Ideas

Natural product-derived therapy for Metastatic human tumors: Magnolin, one of the main components of herb Magnolia fargesii/Flos, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 10/February/2017, 10.55 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]

February 10, 2017

Published by admin_auro at February 10, 2017

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Ideas

Small molecule-based PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: BMP4 (Bone Morphogenetic Protein-4) inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 10/February/2017, 9.52 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]

February 10, 2017

Published by admin_auro at February 10, 2017

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Natural product/vitamin-based Combination therapy for PTEN-deficient cancer: Combination of Eriocitrin, Cholecalciferol and ATRA decreases the expression of the CHD1, increases the expression of a number of tumor suppressor genes, inhibits pro-survival TNF-NF-kB gene network, and suppresses tumorigenesis of PTEN-deficient cancer, 10/February/2017, 8.08 am

Introduction: What they say: A study from the Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA shows that […]

February 9, 2017

Published by admin_auro at February 9, 2017

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Natural product-derived therapy for glucose homeostasis and TIIDM: Celastrol, isolated from herb Thunder God Vine, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 9/February/2017, 10.59 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]