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February 8, 2017
Published by admin_auro at February 8, 2017
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Anti-metastasis therapy: MiRNA-9600 increases the expression of metastasis suppressor Sprouty1 and inhibits proliferation, invasion and metastasis of cancer cells via down regulation of its target gene, 8/February/2017, 10.23 pm

Research findings to Therapeutic opportunity:  The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of metastasis suppressor […]
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February 8, 2017
Published by admin_auro at February 8, 2017
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Natural product-based Lifespan extension therapy: Arecoline/Areca nut extract prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 8/February/2017, 9.25 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
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February 8, 2017
Published by admin_auro at February 8, 2017
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Natural product therapy for pulmonary arterial hypertension: EGCG (Epigallocatechin-3-gallate), one of the main components of Green tea, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 8/February/2017, 8.56 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
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February 8, 2017
Published by admin_auro at February 8, 2017
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Molecular therapy for Bone disorders: MiR-1827 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via down-regulation of its target gene, 8/February/2017, 8.33 am

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone […]
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