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January 17, 2017
Published by admin_auro at January 17, 2017
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Small molecule-based PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: Unacylated ghrelin (UnAG) inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 17/January/2017, 11.35 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
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January 17, 2017
Published by admin_auro at January 17, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Baicalein, isolated from Scutellaria Baicalensis/Lateriflora and Oroxylum indicum among others, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 17/January/2017, 11.17 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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January 17, 2017
Published by admin_auro at January 17, 2017
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Natural product-based Life-extension therapy: Aloe vera inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 17/January/2017, 10.51 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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January 17, 2017
Published by admin_auro at January 17, 2017
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Natural product-based Immune enhancement therapy: Cucrumin, one of the main components of turmeric, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 17/January/2017, 10.27 pm

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
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