Ideas

February 6, 2017
Published by admin_auro at February 6, 2017
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Natural product-based therapy for Metastatic tumors: Formononetin, an isoflavone found in the roots of astragalus membranaceus, Trifolium pratense, Glycyrrhiza glabra, and Pueraria lobata, increases the expression of tumor suppressor interleukin IL1B and promotes apoptosis of tumor cells via down regulation of its target gene, 6/February/2017, 1.40 pm

From Significance of the study to Public health relevance:  Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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February 6, 2017
Published by admin_auro at February 6, 2017
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Molecular therapy for glucose homeostasis and TIIDM: Ethyl Pyruvate (PE) increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 6/February/2017, 5.48 am

Introduction: What they say  A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
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February 5, 2017
Published by admin_auro at February 5, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: BMP4 (Bone Morphogenetic Protein 4) inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 5/February/2017, 11.33 pm

Introduction:What they say: A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 […]
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February 5, 2017
Published by admin_auro at February 5, 2017
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Molecular therapy for Bone disorders: Raf kinase Inhibitor Protein (RKIP) inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 5/February/2017, 11.20 pm

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone […]
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