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Molecular therapy for Myocardial Infarction: Exenatide (brand name: Byetta, & Bydureon), a hypoglycemic agent that functions as a glucagon-like peptide-1 agonist (GLP-1 agonist), inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 21/January/2017, 2.10 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: The Wnt-β-catenin pathway promotes an insulin-sensitized state via up-regulation of its target gene, 21/January/2017, 7.50 am

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
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Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Bergamottin (BGM), a natural Furanocoumarin found in grapefruit juice, increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 20/January/2017, 11.13 pm

From Significance of the study to Public health relevance:  Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Indole-3-carbinol (I3C), found in broccoli, cabbage, cauliflower, brussels sprouts, collard greens and kale, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 20/January/2017, 10.47 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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