Ideas

January 30, 2017

Published by admin_auro at January 30, 2017

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Ideas

Natural product-derived therapy for Metastatic human tumors: Gambogic acid (GA), found in Garcinia hanburyi, decreases the expression of c-Src protein, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 30/January/2017, 12.13 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]

January 30, 2017

Published by admin_auro at January 30, 2017

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Ideas

Cardiac rejuvenation therapy: Special AT‑rich sequence‑binding protein‑1 (SATB1) suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 30/January/2017, 11.13 am

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated […]

January 30, 2017

Published by admin_auro at January 30, 2017

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Ideas

Small molecule-based PD-1 pathway blockade for Human cancer therapy: FK506-binding protein 3 (FKBP3) inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 30/January/2017, 5.45 am

Introduction:What they say: A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 […]

January 30, 2017

Published by admin_auro at January 30, 2017

Categories

Ideas

Molecular therapy for tuberculosis: MiRNA-494-3p increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 30/January/2017, 5.30 am

Introduction: What they say: A study from the Max Plank Institute for Infection Biology, Berlin, Germany shows that “CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in […]