Ideas

December 7, 2016
Published by admin_auro at December 7, 2016
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Ganoderma lucidum extract decreases the expression of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 7/December/2016, 10.27 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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December 7, 2016
Published by admin_auro at December 7, 2016
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Natural product-derived therapy for Myocardial Infarction: Kavalactone (2′,6′-dichloro-5-methoxymethyl-5,6-dehydrokawain), found in herb kava kava, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS , 7/December/2016, 11.18 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 6, 2016
Published by admin_auro at December 6, 2016
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Cardiac rejuvenation therapy: MECP2 (Methyl-CpG-binding protein 2), a transcriptional suppressor, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 6/December/2016, 10.02 pm

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated […]
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December 6, 2016
Published by admin_auro at December 6, 2016
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Natural product-based therapy for Cardiomyopathy: Methyl 3,5-dicaffeoyl quinate (MDQ), found in Salicornia herbacea L, and Aster Ohrai among others, induces the expression of Trbp/miR-208, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 6/December/2016, 9.53 pm

Introduction: What they say: A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, […]
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