Ideas

November 5, 2016
Published by admin_auro at November 5, 2016
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Natural product-based PD-1 pathway blockade for Human cancer therapy: Hibiscus syriacus extract inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 5/November/2016, 10.37 am

Introduction:What they say:  A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 […]
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November 4, 2016
Published by admin_auro at November 4, 2016
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Natural product therapy for Oropharyngeal candidiasis (OPC): Rhamnetin, a flavonoid found in Cloves, increases IL-17R and antimicrobial peptide ß-defensin 3 (BD3, Defb3) expression and promotes resistance against infections caused by Candida albicans via up-regulation of its target gene, 4/November/2015, 11.07 pm

Introduction: What they say A study from the Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; and Department of Mucosal and […]
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November 4, 2016
Published by admin_auro at November 4, 2016
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Natural product-based therapy against Pulmonary bacterial pathogens: Rhamnetin, a flavanoid found in Cloves, increases IL-17R and Chemokine CXCL5 expression and protects against infections caused by bacterial pathogen K. pneumoniae via upregulation of its target gene, 4/November/2015, 10.56 pm

Introduction: What they say A study from the Richard King Mellon Foundation Institute for Pediatric Research, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA […]
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November 4, 2016
Published by admin_auro at November 4, 2016
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Natural product Anti-telomerase cancer therapy: Hesperetin, found in citrus fruits, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 4/November/2016, 10.35 pm

What they say: Introduction:  The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates […]
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