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January 17, 2017
Published by admin_auro at January 17, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Baicalein, isolated from Scutellaria Baicalensis/Lateriflora and Oroxylum indicum among others, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 17/January/2017, 11.17 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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January 17, 2017
Published by admin_auro at January 17, 2017
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Natural product-based Life-extension therapy: Aloe vera inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 17/January/2017, 10.51 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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January 17, 2017
Published by admin_auro at January 17, 2017
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Natural product-based Immune enhancement therapy: Cucrumin, one of the main components of turmeric, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 17/January/2017, 10.27 pm

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
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January 17, 2017
Published by admin_auro at January 17, 2017
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Anticancer therapy targeting the cancer stem cells: MiRNA-9600 increases the expression of tumor suppressor PTEN, suppresses proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 17/January/2016, 10.09 pm

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by increasing the expression of its target genes, it may increase the expression of tumor suppressor PTEN. […]
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