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January 14, 2017
Published by admin_auro at January 14, 2017
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Anticancer therapy targeting the cancer stem cells: MiRNA-9600 inhibits the expression of stem cell gene Oct-4, inhibits proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 14/January/2016, 4.55 pm

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by increasing the expression of its target genes, it may decrease the expression of the protein enriched […]
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January 14, 2017
Published by admin_auro at January 14, 2017
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Life-extension therapy: Nateglinide, a blood glucose-lowering drug, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 14/January/2017, 4.29 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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January 13, 2017
Published by admin_auro at January 13, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Persimmon tannin extract decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 13/December/2016, 11.45 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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January 13, 2017
Published by admin_auro at January 13, 2017
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Natural product-derived therapy for Metastatic human tumors: Boehmenan, a lignan from the Chinese medicinal plant Clematis armandi, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 13/January/2017, 11.27 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
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