Ideas

January 17, 2017
Published by admin_auro at January 17, 2017
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Natural product-based Immune enhancement therapy: Cucrumin, one of the main components of turmeric, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 17/January/2017, 10.27 pm

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
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January 17, 2017
Published by admin_auro at January 17, 2017
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Anticancer therapy targeting the cancer stem cells: MiRNA-9600 increases the expression of tumor suppressor PTEN, suppresses proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 17/January/2016, 10.09 pm

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by increasing the expression of its target genes, it may increase the expression of tumor suppressor PTEN. […]
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January 16, 2017
Published by admin_auro at January 16, 2017
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Natural product-derived therapy for Myocardial Infarction: Tyrosol, found in Olive oil and argan oil among others, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 16/January/2017, 11.59 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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January 16, 2017
Published by admin_auro at January 16, 2017
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Natural product-derived therapy for Human Leukemias: Manumycin A, an antibiotic that acts as an inhibitor of farnesyltransferase (FTase), suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 16/January/2016, 11.45 pm

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms […]
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