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January 4, 2017
Published by admin_auro at January 4, 2017
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Vitamin-based Cardiac rejuvenation therapy: Ascorbic acid suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 4/January/2017, 3.20 pm

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated […]
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January 4, 2017
Published by admin_auro at January 4, 2017
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Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: Matrine, isolated from Sophora flavescens, inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 4/January/2017, 3.06 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
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January 4, 2017
Published by admin_auro at January 4, 2017
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Vitamin therapy for overcoming chemoresistance in Human cancers: δ-tocotrienol (a form of Vitamin-E) increases the expression of CADM1, decreases BMI1 translocation, increases tumor suppressor INK4a/p16 expression and restores chemosensitivity in drug-resistant Human cancers via down regulation of its target gene, 4/January/2016, 12.15 pm

From Research findings to Therapeutic opportunity:  The study presented here suggests that δ-tocotrienol, by increasing the expression of its target genes, it may: (i) increase the expression of CADM1; […]
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January 4, 2017
Published by admin_auro at January 4, 2017
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Natural product-derived therapy for H. pylori–induced Gastric cancer: Amla extract inhibits WNT-SOX9 pathway, decreases oncogenic β-catenin levels, suppresses H. pylori-induced gastric cancer proliferation, inhibits acquisition of tumor-initiating stem-cell properties and decreases chemoresistance via up regulation of its target gene, 4/January/2017, 5.48 am

From Research findings to Therapeutic opportunity:  The study presented here suggests that Amla extract, by increasing the expression of its target genes, it may: (i) inhibit WNT-SOX9 oncogenic pathway; […]
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