Ideas

December 26, 2016
Published by admin_auro at December 26, 2016
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Molecular therapy for Myocardial Infarction: PF-4708671, an inhibitor of p70 ribosomal S6 kinase 1, inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 26/December/2016, 9.33 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 25, 2016
Published by admin_auro at December 25, 2016
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Molecular therapy for Myocardial Infarction: Verapamil, a calcium channel blocker and an antihypertensive drug, inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 25/December/2016, 11.19 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 25, 2016
Published by admin_auro at December 25, 2016
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Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: Honokiol, isolated from Magnolia-grandiflora/dealbata/obovata/officinalis, inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 25/December/2016, 10.37 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
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December 25, 2016
Published by admin_auro at December 25, 2016
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Natural product-derived therapy for enhancing anti-cancer immunity: Emodin (6-methyl-1,3,8-trihydroxy anthraquinone), found in Polygonum multiflorum, decreases the level of LATS1/2 (large tumor suppressor 1 and 2), increases immunogenicity of tumors, enhances anti-tumor immune responses, and inhibits tumor growth via down regulation of its target gene, 25/December/2016, 10.00 pm

Introduction: What they say:  A study from the Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA shows that […]
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