Ideas

December 9, 2016
Published by admin_auro at December 9, 2016
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Natural product-derived therapy for Myocardial Infarction: Saponin, found in Panx Japonicus and Soapworts among others, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 9/December/2016, 8.13 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 9, 2016
Published by admin_auro at December 9, 2016
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Anti-telomerase cancer therapy: MiRNA-362 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 9/December/2016, 6.18 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]
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December 8, 2016
Published by admin_auro at December 8, 2016
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Natural product-derived therapy for brain repair and Lifespan extension: Casticin, found in Vitex agnus-castus, and Artemisia annua, increases VGF and BDNF expression, promotes Oligodendrocytes (OP) proliferation, triggers myelination on neurons, reverts neural damage, produces antidepressant like effects, and prolongs lifespan via up-regulation of its target gene, 8/December/2016, 11.58 pm

What they say: Introduction:   A recent study from the Department of Biochemistry & Molecular Pharmacology, Smilow Research Center, Howard Hughes Medical Institute, NYU School of […]
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December 8, 2016
Published by admin_auro at December 8, 2016
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: N(1), N(11)-Diethylnorspermine (DENSPM), a spermine analog, decreases the expression of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 8/December/2016, 11.31 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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