Ideas

December 14, 2016
Published by admin_auro at December 14, 2016
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Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses. Eriocitrin, isolated from lemons, decreases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 14/December/2015, 7.21 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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December 14, 2016
Published by admin_auro at December 14, 2016
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Mineral-rich water therapy for Myocardial Infarction and Diabetic Nephropathy: Mineral-rich water inhibits DNA damage responses, decreases oxidative stress, inhibits advanced glycation end products, increases telomerase expression, inhibits telomere shortening, promotes cardiomyocyte survival after myocardial infarction and prolongs mammalian life span via up-regulation of PNUTS, 14/December/2016, 13.36 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 14, 2016
Published by admin_auro at December 14, 2016
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Natural product Immune enhancement therapy: Fisetin, isolated from Strawberry, blueberries, mangoes, apples, persimmon, kiwi, onions, grapes and cucumber among others, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 14/December/2016, 8.57 am

Introduction: What they say:  A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils […]
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December 13, 2016
Published by admin_auro at December 13, 2016
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Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Kuwanon V, one of the constituents of Mulberry, increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 13/December/2016, 11.35 pm

From Significance of the study to Public health relevance: Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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