Ideas

December 2, 2016
Published by admin_auro at December 2, 2016
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Natural product-derived therapy for triple-negative breast tumors: Withaferin A, isolated from Withania somnifera/Ashwagandha and Acnistus arborescens among others, increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 2/December/2015, 6.32 pm

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]
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December 2, 2016
Published by admin_auro at December 2, 2016
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Natural product-derived therapy for Myocardial Infarction: Emodin (6-methyl-1,3,8-trihydroxy anthraquinone), found in Polygonum multiflorum, and Japanese knotweed among others, inhibits DNA damage responses, and telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 2/December/2016, 12.15 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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December 2, 2016
Published by admin_auro at December 2, 2016
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Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extend lifespan via up regulation of its target gene, 2/December/2016, 7.04am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that:  Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extends lifespan via up regulation of […]
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December 2, 2016
Published by admin_auro at December 2, 2016
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Molecular therapy for Metabolic disorders: PNUTS (a protein phosphatase) increases (LXR)-α expression, insulin-secreting cell mass and function via down regulation of its target genes, 2/December/2016, 7.01 am

Public health relevance:  Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to treat […]
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