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December 20, 2016
Published by admin_auro at December 20, 2016
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Natural product-derived therapy for enhancing anti-cancer immunity: Hesperidin, found abundantly in Citrus fruits, decreases the level of LATS1/2 (large tumor suppressor 1 and 2), increases immunogenicity of tumors, enhances anti-tumor immune responses, and inhibits tumor growth via down regulation of its target gene, 20/December/2016, 6.27 pm

Introduction: What they say:  A study from the Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA shows that […]
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December 20, 2016
Published by admin_auro at December 20, 2016
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Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: Rhamnetin, an O-methylated flavonoid isolated from herb Cloves, inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 20/December/2016, 3.00 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
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December 20, 2016
Published by admin_auro at December 20, 2016
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Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: American ginseng increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 20/December/2016, 11.46 am

From Significance of the study to Public health relevance: Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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December 19, 2016
Published by admin_auro at December 19, 2016
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Immune enhancement therapy: HIF-2α increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 19/December/2016, 10.14 pm

Introduction: What they say:  A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils […]
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