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December 10, 2016
Published by admin_auro at December 10, 2016
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Natural product-derived therapy for triple-negative breast tumors: Cucurbitacin D, found in Trichosanthes kirilowii (Gualou), Phormium tenax, and Luffa amara among others, increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 10/December/2016, 7.21 pm

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]
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December 10, 2016
Published by admin_auro at December 10, 2016
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Moringa Olifera extract decreases the expression of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 10/December/2016, 6.34 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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December 10, 2016
Published by admin_auro at December 10, 2016
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Anti-telomerase cancer therapy: Cancer suppressor VHL (Von Hippel-Lindau) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 10/December/2016, 11.53 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]
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December 10, 2016
Published by admin_auro at December 10, 2016
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Natural product-derived therapy for overcoming chemoresistance in Human cancers: Amla extract increases the expression of CADM1, decreases BMI1 translocation, increases tumor suppressor INK4a/p16 expression and restores chemosensitivity in drug-resistant Human cancers via down regulation of its target gene, 10/December/2016, 8.51 am

What is known? I have published earlier that Amla extract: (i) increases the levels of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, […]
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