Ideas

December 2, 2016
Published by admin_auro at December 2, 2016
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Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extend lifespan via up regulation of its target gene, 2/December/2016, 7.04am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that:  Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extends lifespan via up regulation of […]
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December 2, 2016
Published by admin_auro at December 2, 2016
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Molecular therapy for Metabolic disorders: PNUTS (a protein phosphatase) increases (LXR)-α expression, insulin-secreting cell mass and function via down regulation of its target genes, 2/December/2016, 7.01 am

Public health relevance:  Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to treat […]
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December 1, 2016
Published by admin_auro at December 1, 2016
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Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses: Cucurbitacin E, found abundantly in Watermelons, decreases spermidine/spermine N1-acetyltransferase (SAT1) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 1/December/2015, 8.13 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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December 1, 2016
Published by admin_auro at December 1, 2016
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Natural product-based cardioprotective therapy: Lycium barbarum polysaccharide (LBP) increases Spermidine levels, augments autophagy, mitophagy and mitochondrial respiration, lowers systemic blood pressure, and protects it from cardiac diseases via down regulation of its target gene, 1/December/2016, 2.40 pm

Introduction: What they say A study from the Institute of Molecular Biosciences, University of Graz, Humboldtstraße 50, A-8010 Graz shows that “Cardioprotection and lifespan extension by […]
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