Ideas – Page 888

November 21, 2016

Published by admin_auro at November 21, 2016

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MiRNA-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients: MiRNA-96 increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 21/November/2016, 8.10 pm

[easy_payment]Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte […]

November 21, 2016

Published by admin_auro at November 21, 2016

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Natural product-based PD-1 pathway blockade for Human cancer therapy: γ-Bisabolene, found in Cardamom among others, decreases the expression of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 21/November/2016, 11.17 am

Introduction:What they say: A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]

November 21, 2016

Published by admin_auro at November 21, 2016

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Molecular therapy for Metabolic disorders: MiRNA-208-3p increases (LXR)-α expression, insulin-secreting cell mass and function via down regulation of its target genes, 21/November/2016, 11.04 am

Significance of the study: Given that (1) more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to […]

November 21, 2016

Published by admin_auro at November 21, 2016

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Anti-metastasis therapy: MiRNA-9600 increases the expression of tumor suppressor PTEN and inhibits proliferation, invasion and metastasis of cancer cells via down regulation of its target gene,21/November/2015, 10.38 am

Research findings to Therapeutic opportunity: The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of tumor suppressor […]