Ideas

May 17, 2015

Natural product-based therapy for pulmonary arterial hypertension: Scopoletin, found in chicory, in Artemisia scoparia, in Stinging Nettle, and in the passion flower, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 17/May/2015, 15.33

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
May 16, 2015

MiRNA-based therapy for p53-deficient tumors: IAPP (Amylin) increases the expression of tumor suppressor MiRNA-34 and induces regression of p53-mutated human tumors via up regulation of its target gene, 16/May/2015, 23.49

A recent study from the Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [2] […]
May 13, 2015

Regenerating the lost pancreatic β-cells in Diabetic patients: 6-Gingerol, a pungent component of Ginger, promotes an insulin-sensitized state via up regulation of reprogramming protein Lin28, 13/May/2015, 12.40 pm

A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates […]
May 13, 2015

Natural product-based therapy for Cancer cachexia: Piceatannol, a natural compound found in passion fruit, inhibits muscle fiber atrophy during cancer cachexia and sepsis and promotes muscle growth via up regulation of its target gene, 13/May/2015, 12.22 pm

Significance: Muscle atrophy is associated with a number of disease conditions, including sepsis, Cancer cachexia etc. This study suggests, for the first time, that Piceatannol, by increasing the expression […]
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