Ideas

October 20, 2016

Natural product therapy for tuberculosis: Avacado (Persea Americana) fruit extract increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 20/October/2016, 10.51 pm

A study from the Max Plank Institute for Infection Biology, Berlin, Germany shows that “CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.” This study […]
October 20, 2016

Natural product Antisepsis therapy: Epigallocatechin gallate, one of the components in green tea, increases Sestrin2 expression, inhibits NLRP3 inflammasome activation, and pro-inflammatory cytokines secretion, induces mitophagy in macrophages, and clears damaged mitochondria via autophagic machinery, and protects the host from sepsis via up- regulation of its target gene, 20/October/2016, 10.05 pm

A recent study from the Yonsei University College of Medicine, Seoul, Korea shows that Sestrin2 suppresses Sepsis by inducing mitophagy and inhibiting NLRP3 activation. This study […]
October 20, 2016

Natural product therapy targeting aberrant Lipid synthesis in Human cancers: Withaferin A, isolated from Withania somnifera (Ashwagandha), suppresses the expression of the principal enzyme in lipid synthesis, ACLY, inhibits aberrant lipid production, and tumor progression via up regulation of its target gene, 20/October/2016, 8.54 pm

A recent study from Rutgers Cancer Institute of New Jersey, Rutgers University, The State University of New Jersey, New Brunswick, New Jersey, USA shows that “Cullin3–KLHL25 ubiquitin […]
October 20, 2016

Natural product Immune enhancement therapy: Stinging nettle extract increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 20/October/2016, 7.57 am

A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity […]
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