Ideas

October 28, 2016
Published by admin_auro at October 28, 2016
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Small molecule-based PD-1 pathway blockade for Human cancer therapy: DEAR1/TRIM62 inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 29/october/2016, 11. 30 am

Introduction:What they say: A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 […]
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October 28, 2016
Published by admin_auro at October 28, 2016
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Natural product therapy for brain repair and Life-span extension: Ursolic acid, found in Tulsi and apple peels, among others, increases VGF and BDNF expression, promotes Oligodendrocytes (OP) proliferation, triggers myelination on neurons, reverts neural damage, produces anti-depressant like effects, and prolongs lifespan via up-regulation of its target gene, 28/October/2016, 9.29 pm

What they say: Introduction:   A recent study from the Department of Biochemistry & Molecular Pharmacology, Smilow Research Center, Howard Hughes Medical Institute, NYU School of […]
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October 28, 2016
Published by admin_auro at October 28, 2016
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Natural product Lifespan extension therapy: Thermostable extract of fenugreek seeds increases life span via up-regulation of its target gene BubR1, 28/October/2016, 3.04 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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October 28, 2016
Published by admin_auro at October 28, 2016
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Natural product therapy for tuberculosis: α-Lipoic acid, found in broccoli, yams, tomatoes, Brussels sprouts, carrots, and rice bran, among others, increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 28/October/2016, 2.46 pm

Introduction: A study from the Max Plank Institute for Infection Biology, Berlin, Germany shows that “CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.” This […]
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