Ideas

October 15, 2016
Published by admin_auro at October 15, 2016
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Life-extension therapy: MiR-451 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 15/October/2016, 9.03 am

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 […]
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October 15, 2016
Published by admin_auro at October 15, 2016
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Molecular therapy for Metabolic disorders: MiRNA-200a-3p increases (LXR)-α expression, decreases triglyceride and cholesterol levels, increases insulin sensitivity and promotes leanness via down regulation of its target genes, 15/October/2016, 6.50 am

Significance:  Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to treat DM; and […]
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October 14, 2016
Published by admin_auro at October 14, 2016
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Molecular therapy for Pulmonary Fibrosis: Chenodeoxycholic acid increases Toll-like receptor 4 expression and extracellular matrix glycosaminoglycan Hyaluronan levels, promotes alveolar progenitor cell renewal and repair of lung injury and prevents severe pulmonary fibrosis via down-regulation of its target gene, 14/October/2016, 10.48 pm

A study from the Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA; and Women’s Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA […]
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October 14, 2016
Published by admin_auro at October 14, 2016
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Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Theobromine, a compound derived from theobroma; and commonly found in chocolates, increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 14/October/2015, 10.32 pm

A study from the Center for Inflammation, Immunity &Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA shows that: “Resveratrol suppresses NTHi-induced inflammation […]
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