Ideas

May 3, 2015

Molecular therapy for Metastatic human tumors: Ndfip1 inhibits cellular proliferation, invasion and metastasis by increasing the expression of metastasis suppressor KRIT1/CCM1 via down regulation of its target gene, 3/May/2015, 23.22

A study from the Cell Pathology Division, The Children’s Hospital of Philadelphia, Philadelphia, USA shows that “TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production […]
May 1, 2015

Stretch therapy for pulmonary arterial hypertension: Mechanical stretch inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/May/2015, 9.01 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
April 30, 2015

Anti-metastasis therapy: MiRNA-134 increases the expression of TPM1 (tropomyosin) and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 30/April/2015, 18.19

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Anti-metastasis therapy: MiRNA-134 increases the expression of TPM1 (tropomyosin) and inhibits migration and invasion of […]
April 26, 2015

Molecular cancer therapy: JunB inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 26/April/2015, 17.16

A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.  This study was published in the April 10, 2014 Nature [I.F >42] by Prof. Thomas H, […]
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