Ideas

April 19, 2015
Published by admin_auro at April 19, 2015
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Sunlight exposure stalls p53-mutated metastatic cancer progression: Calcitriol (1α, 25-dihydroxyvitamin D3) increases the expression of tumor suppressor p53 homolouge TAp63 and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 19/April/2015, 10.43 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance:  Cancer suppressor p53 is mutated in more than 50% of human cancers of different origin, while its pathway […]
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April 5, 2015
Published by admin_auro at April 5, 2015
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Natural product-based cancer therapy: Ursolic acid, enriched in apples, inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 5/April/2015, 14.23

A study from Karolinska Institutet, Stockholm, Sweden shows that “MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.” This study was published in the April 10, 2014 Nature [I.F >42] by Prof. Thomas […]
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April 1, 2015
Published by admin_auro at April 1, 2015
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Natural product-based Lifespan extension therapy: Piceatannol, a natural compound found in passion fruit (Passiflora edulis), may prolong mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 1/April/2014, 22.03

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Natural product-based Lifespan extension therapy: Piceatannol, a natural compound found in passion fruit (Passiflora edulis), may prolong […]
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March 20, 2015
Published by admin_auro at March 20, 2015
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Natural-product based therapy for Sepsis: Piceatannol, a natural compound found in passion fruit (Passiflora edulis), inhibits lung inflammation by inhibiting inflammasome activation pathway, 20/March/2014, 09.27 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Natural-product based therapy for Sepsis:  Piceatannol,  a natural compound found in passion fruit (Passiflora edulis),  inhibits lung inflammation by […]
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