November 5, 2017

Natural product-derived Life-extension therapy: Andrographolide, isolated from the stem and leaves of Andrographis paniculata, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 5/November/2017, 11.00 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
November 4, 2017

Natural product-based combinatorial therapy for ageing-associated diseases and Lifespan extension: A therapeutic mix encompassing Glycyrrhetinic acid, Ginsenoside and 4-Bromoflavone (GGB) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 4/November/2017, 11.51 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
November 1, 2017

Lifespan extension therapy:  4-Hydroxyderricin (4-HD), isolated from Ashitaba (Angelica Keiskei), increases life span via up-regulation of its target gene BubR1, 1/November/2017, 11.41 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
October 31, 2017

Molecular therapy for TIIDM and Metabolic defects: Ezetimibe (Trade name: Zetia or Ezetrol), a cholesterol lowering medication, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 31/October/2017, 11.11 am

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]