Longevity

August 31, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Baicalein, DIM, and Cholecalciferol activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 1/September/2017, 1.46 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 31, 2017

 Life-extension therapy: N-Acetyl cysteine (NAC) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 1/September/2017, 12.52 am

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
August 30, 2017

Lifespan extension therapy: Olmesartan, a drug used in the treatment of high blood pressure,  prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 30/August/2017, 11.52 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
August 29, 2017

 Lifespan extension therapy: Ruxolitinib (Trade name: Jakavi), a drug used in the treatment of Myelofibrosis,  prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 30/August/2017, 12.06 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]