Consume chocolates to protect yourself from Myocardial Infarction: Theobromine/xantheose, derived from theobroma and commonly found in chocolates, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 22/December/2014, 8.40 am

Consume chocolates to protect yourself from Myocardial Infarction: Theobromine/xantheose, derived from theobroma and commonly found in chocolates, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 22/December/2014, 8.40 am

Consume chocolates to protect yourself from Myocardial Infarction: Theobromine/xantheose, derived from theobroma and commonly found in chocolates, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 22/December/2014, 8.40 am 150 150

A recent study from the Institute for Cardiovascular RegenerationCentre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature [I.F: >42] by Prof Dimmler, Boon, and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Consume chocolates to protect yourself from  Myocardial Infarction: Theobromine/xantheose, derived from theobroma and commonly found in chocolates, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10). It has been shown earlier that consuming chocolates can protect one from myocaridal diseases. However, the mechanistic insight into how chocolate protects one from myocaridal diseases is far from clear. This study suggests, for the first time, that thebromine, a chocolate-derived compound, by increasing the expression of PNUTS, it may inhibit DNA damage responses, telomere shortening; and promote cardimyocyte survival. Therefore, by treating people with Theobromine, one may prevent ageing-associated decline in cardiac function.  Together, this study suggests, for the first time, that pharmacological formulations encompassing Theobromine  or its analogues” may be used to improve cardiac function after myocardial infarction. Based on this finding, Physicians may consider encouraging their cardiac patients to consume limited amount of chocolates, to protect themselves from heart diseases. 

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan,  Consume chocolates to protect yourself from  Myocardial Infarction: Theobromine/xantheose, derived from theobroma and commonly found in chocolates, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 22/December/2014,  8.39 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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