Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., GOD can extend your life span: Celastrol, an antioxidant compound isolated from herb Thunder of GOD vine, inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5/AC5), 11/March/2014, 15.57, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that Celastrol, a natural compound isolated from herb Thunder of God vine, may extend the lifespan of an individual by suppressing ADCY5/AC5 expression. Thus, pharmacological formulations encompassing “Celastrol or its analogues” may be used to extend the lifespan of an an individual.
Undisclosed information: How Celastrol suppresses the expression of adenylate cyclase 5 (ADCY5)