Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., GOD can extend your life span: Celastrol, an antioxidant compound isolated from herb Thunder of GOD vine, inhibits senescence and extends life span by down regulating the expression of mTOR, 13/March/2014, 5.40 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: It has been shown earlier that decreasing the expression of mTOR increases overall lifespan. This study suggests, for the first time, that Celastrol, a natural compound isolated from herb Thunder of God vine, may extend the lifespan of an individual by suppressing mTOR expression. Thus, pharmacological formulations encompassing “Celastrol or its analogues” may be used to extend the lifespan of an an individual.
Undisclosed information: How Celastrol suppresses the expression of mTOR