Bio-Med Ideas

April 12, 2015

Natural product-based therapy for pulmonary arterial hypertension: Betulinic acid, an anticancer agent isolated from birch tree, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 12/April/2015, 9.41 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
April 12, 2015

Natural product-based Life-span extension therapy: Licochalcone A (LA), a flavanoid isolated from licorice (Glycyrrhiza glabra) root, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 12/April/2015, 8.58 am

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 […]
April 11, 2015

Therapeutic insights into the treatment of Stress-induced heart failure: 5-aminoimidazole-4-carboxamide riboside (AICAR), an analog of AMP, protects against stress-induced heart failure via up regulation of SNX13, 11/April/2015, 22.22

A recent study from the Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai 200120, China shows that “SNX13 reduction […]
April 11, 2015

MiRNA-based therapy for Lipid metabolism disorders: TGF-β1 inhibits the expression of IDH1 and lipid accumulation via up regulation of its target gene, 11/April/2015, 22.12

A study from the CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences, University of Science & […]
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