Bio-Med Ideas

May 1, 2015

A known drug of an unknown function as an inhibitor of lipid accumulation and redistribution: Metformin, the widely used drug in the treatment of T2DM, inhibits lipid biosynthesis and lipid droplet formation via down regulation of its target gene, 1/May/2014, 11.27 am

A recent study from the International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Department of Pathology & Pathophysiology, School […]
May 1, 2015

Stretch therapy for pulmonary arterial hypertension: Mechanical stretch inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/May/2015, 9.01 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
April 30, 2015

The Exercise-Mimicking pills may inhibit Insulin resistance and decrease adiposity: BMB4 decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, improves muscle insulin sensivitity and decreases adiposity via up regulation of its target gene, 1/May/2015, 12.19 am

Significance: This study suggests, for the first time, that BMP4, by increasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
April 30, 2015

Turning on senescence turns off cancer progression: HIF-1α inhibits telomere dysfunction and senescence via up regulation of Telomeric repeat binding factor 2 (TRF2), 30/April/2015, 23.57

A recent study from the Key Laboratory of Gene Engineering of the Ministry of Education, Key Laboratory of Reproductive Medicine of Guangdong Province, School of Life Sciences […]
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