Bio-Med Ideas

May 3, 2015

Molecular therapy for Metastatic human tumors: Ndfip1 inhibits cellular proliferation, invasion and metastasis by increasing the expression of metastasis suppressor KRIT1/CCM1 via down regulation of its target gene, 3/May/2015, 23.22

A study from the Cell Pathology Division, The Children’s Hospital of Philadelphia, Philadelphia, USA shows that “TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production […]
May 3, 2015

Regenerating the lost cardiomyocytes in Myocardial patients: MiRNA-582-5p increases the expression of ERBB2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 3/May/2014, 23.12

A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
May 3, 2015

Natural product-based Regenerative therapy for Diabetes mellitus: Grape skin ethanol extract increases human pancreatic beta cell replication via down regulation of its target gene DYRK1A, 3/May/2015, 22.38

A study from the Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA and Division of Endocrinology and Bone […]
May 3, 2015

Stalling metastatic cancer spread by exposing it to the Sunlight: Calcitriol (1α, 25-dihydroxyvitamin D3) increases the expression of tumor suppressor GAS5 and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 3/May/2015, 22.23

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-metastasis therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its target genes, […]
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