Bio-Med Ideas

April 19, 2015

Small molecule-based Life-span extension therapy: Endothelin-1 (ET-1) inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 19/April/2015, 10.37 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Small molecule-based Life-span extension therapy: Endothelin-1 (ET-1) inhibits senescence and  extends life span by down regulating […]
April 19, 2015

Immune enhancement therapy: ARID3B (AT rich interactive domain 3B) increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 19/April/2015, 06.16 am

A recent study from the Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor […]
April 19, 2015

Rescuing the malfunctioning cardiomyocytes in myocardial patients: E3 ubiquitin ligase RNF2 (ring finger protein 2) improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 19/April/2014, 06.09 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On […]
April 18, 2015

Natural product-based therapy for pulmonary arterial hypertension: Sasa quelpaertensis Nakai inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 19/April/2015, 12.10 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
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