Bio-Med Ideas

January 4, 2019

RNA-based therapy for aging-associated diseases and Lifespan extension: LncRNA BRM inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 4/January/2019, 10.03 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
January 4, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced mutant p53-expressing metastatic cancers: A pharmaceutical mixture encompassing  Mibolerone (Trade name: Cheque drops and Matenon), an anabolic-androgenic steroid,  and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as LATS1, SMARCA4, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 4/January/2018, 9.51 am

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that:  Probiotic-based chemotherapy targeting cancer stem cells […]
January 4, 2019

RNA-based therapy for Diabetes: LncRNA TUG1 increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 4/January/2019, 9.31 am

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, the University of Alabama at […]
January 1, 2019

The miracle spice Cinnamon may help you live longer: Cinnamon-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Cinnamoldehyde, Ursolic acid, Catalpol, Isoliquiritigenin, Maresin, DIM, Ursolic acid  Lutein, Maresin, Cholecalciferol (UCIMDULMC) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan, via up regulation of its target gene ATG5 (Autophagy related 5), 2/January/2018, 12.01 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
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