Bio-Med Ideas

January 16, 2019

Mechanistic insights into how Fasudil functions as a learning/memory/cognitive-enhancer:  Fasudil (brand name: hydroxyfasudil), a vasodilator used in the treatment of pulmonary hypertension, stroke and others, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down-regulation of its target genes, 16/January/2019, 11.18 pm

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
January 15, 2019

Urine-derived compound functions as a longevity promoter: Ulinastatin (trade name: Miraclid, Ulinase, U-Tryp,Bikunin and Urinastatin), a trypsin inhibitor found in human urine and used in the treatment of  acute/chronic pancreatitis, burns and others, slows down cardiac aging, and increases lifespan, via up-regulation of BubR1 and others genes, 16/January/2019, 12.51 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]
January 15, 2019

RNA-based therapy for aging-associated diseases and Lifespan extension: LncRNA PRLB  inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 15/January/2019, 11.58 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
January 15, 2019

Natural product-based anti-ageing and Lifespan extension therapy:  A pharmaceutical mixture encompassing Celecoxib and quercetin (CQ) increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan, via down regulation of its target gene, 15/January/2019, 11.47 pm

Introduction: What they say  A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
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