Bio-Med Ideas

December 1, 2018

Cancer therapy targeting cancer stem cells in chronic myelogenous leukemia (CML) and other metastatic cancers: Misoprostol, an FDA-approved EP4 agonist and abortion-promoting drug, increases the expression of tumor suppressor genes, such as p12DOC1/CDK2AP1, SMAD7, p53, and TA-p73/p63, targets CML leukemic stem cells, confers protection against CML and prolongs survival, via up-regulation of its target gene, 1/December/2018, 11.52 pm

Introduction: What they say: A study from the Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA shows […]
December 1, 2018

Probiotics function as anti-HIV agents: Probiotic Lactobacillus rhamnosus increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 12/November/2018, 11.00 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Probiotics function as anti-HIV agents: Probiotic Lactobacillus rhamnosus increases Heme oxygenase 2 (HO-2) expression, blocks […]
December 1, 2018

Steroid-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:  Prostaglandin E2 (PGE2)/ Dinoprostone (Trade name: PGE2, Cervidil, Propess, others) increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via down-regulation of its target gene, 1/December/2018, 7.47 am

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
December 1, 2018

 A probiotic way to plummet depression and anxiety:  Probiotic Lactobacillus helveticus NS8 decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 1/December/2018, 7.33 am

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
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