Bio-Med Ideas

June 7, 2019

Molecular therapy for body weight control, energy homeostasis and TIIDM: Aleglitazar, a PPARα and PPARγ agonist, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 7/June/2019, 11.30 pm

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
June 7, 2019

Why Chronic stress-induced depression is not good for your heart: Mechanistic insights into chronic stress-induced depression may accelerate cardiac dysfunction: Chronic stress-induced depression augments DNA damage responses, attenuates telomerase expression, promotes telomere shortening, and attenuates cardiomyocyte survival after myocardial infarction, via down regulation of PNUTS, 7/June/2018, 11.01 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of […]
June 6, 2019

Sesame oil-derived compounds promote lifespan-extension: Sesamin/sesamol-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Sesamin, sesamol, Melatonin, Ursolic acid, Maresin, DIM, Lutein, Ursolic acid  Lutein, Maresin, Cholecalciferol  Catalpol, Isoliquiritigenin (SSMUMDLCCI) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via upregulation of its target gene ATG5 (Autophagy-related 5), 6/June/2019, 11.24 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
June 5, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as TPM1, CADM1/2, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 05/June/2019, `7.17 am

Introduction: What they say A study from the University of Texas M.D. Anderson Cancer Center, Houston, USA shows that “Ibrutinib and Venetoclax for First-Line Treatment of CLL.” This research […]
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